Os30

SKU: orb1943169

Description

Os30 is a potent fourth-generation EGFR inhibitor targeting the EGFR C797S mutation, with IC50 values of 18 nM and 113 nM for common triple-mutant variants. It inhibits phosphorylation, induces cell cycle arrest and apoptosis in vitro, and demonstrates antitumor activity in NSCLC models harboring EGFR C797S mutations.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• Target: EGFR,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR,Apoptosis