OS-3-106

SKU: orb1298491

Description

OS-3-106

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1580000-17-4
• MW: 450.6
• Purity: 97.71% (May vary between batches)
• Formula: C₂₅H₃₀N₄O₂S
• SMILES: COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(cc2)-c2cscn2)CC1
• Target: Dopamine Receptor
• Solubility: DMSO:4.51 mg/mL (10.01 mM)

Bioactivity

• Target IC50:
  D3 receptor:0.2 nM (Ki)
• In Vitro:
  The effect of OS-3-106 (10 mg/kg) on the dose-response function of cocaine self-administration. OS-3-106 decreased cocaine and sucrose reinforcement rates, increased latency to first response for cocaine but not sucrose, and downshifted the cocaine self-administration dose-response function. Thish compounds blocked a D3R-mediated behavior.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, HEK 293 cells, arylamide phenylpiperazine, Dopamine Receptor, DopamineReceptor, D3, cocaine, OS 3 106, OS3106, OS-3-106, self-administration, psychostimulant addiction, sucrose

Compound Identifiers

PubChem CID

91885413