ORIC-533

SKU: orb2565612

Description

ORIC-533 is an orally bioavailable, competitive CD73 inhibitor that reactivates suppressed CD8+ T cells. It demonstrates potent anti-multiple myeloma activity by inducing tumor cell lysis within the bone marrow niche, as shown in preclinical in vitro and in vivo studies.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 2641306-62-7
• MW: 605.93
• Formula: C₂₀H₂₉ClN₉O₉P
• SMILES: O[C@H]1[C@H](N2C=3C(C=N2)=C(NC4CCCC4)N=C(Cl)N3)O[C@H](CO[C@](COCC=5NN=NN5)(P(=O)(O)O)CO)[C@H]1O
• Target: CD73

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156311996