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OBX02-011

SKU: orb2647577

Description

OBX02-011 is a potent, reversible, fourth-generation EGFR tyrosine kinase inhibitor (TKI) that overcomes the EGFR C797S mutation, inhibits triple mutants Del19/T790M/C797S and L858R/T790M/C797S with IC50 of 0.134 and 2.09 nM, respectively.

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Key Properties

CAS Number2349336-18-9
MW615.189763307571
Purity>98%
FormulaC29H39CLN8O3S
SMILESClC1C=NC(=NC=1NC1C=CC=CC=1N(C)S(C)(=O)=O)NC1C=CC(=CC=1OC)N1CCC(CC1)N1CCN(C)CC1

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

OBX02-011 (orb2647577)

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