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O6-Methyldeoxy guanosine

SKU: orb1907473

Description

O6-Methyldeoxyguanosine is a modified purine nucleoside that acts as a weak inhibitor of O6-methylguanine repair by rat liver enzymes in vitro. It is used in DNA repair studies, particularly to investigate the mechanisms of alkylation damage and the function of MGMT in both in vitro and in vivo research contexts.

Research Area

Cell Biology, Molecular Biology

Images & Validation

Key Properties

CAS Number964-21-6
MW281.27
FormulaC11H15N5O4
SMILESO(C)C1=C2C(N(C=N2)[C@@H]3O[C@H](CO)[C@@H](O)C3)=NC(N)=N1
TargetOthers
SolubilityDMSO:80 mg/mL (284.42 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (11.73 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

6-O-Methyldeoxyguanosine, O6-Methyl-2'-deoxyguanosine
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Key Properties

No computed properties available.

Protocol Information