O-Desmethyl gefitinib (Standard)

SKU: orb3141144

Description

O-Desmethyl gefitinib (Standard) is a reference standard for research and analysis in studies involving O-Desmethyl gefitinib. O-Desmethyl gefitinib inhibits EGFR (IC50: 36 nM in subcellular assays). In human plasma, O-Desmethyl gefitinib is an active metabolite of Gefitinib. The formation of O-desmethyl gefitinib is dependent on the CYP2D6 activity.

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Key Properties

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CAS Number	847949-49-9
MW	432.88
Formula	C₂₁H₂₂ClFN₄O₃
SMILES	Oc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1
Target	Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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