Nutlin-C1-amido-PEG4-C2-N3

SKU: orb1988394

Description

Nutlin-C1-amido-PEG4-C2-N3 is a PROTAC linker-ligand conjugate featuring an MDM2-binding Nutlin derivative. It is utilized in the development of bifunctional degraders for cancer research, enabling the targeted degradation of proteins in both cellular and preclinical models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• MW: 883.82
• Formula: C₄₂H₅₂Cl₂N₈O₉
• SMILES: O=C(CN(C(N1C(C2=CC=C(OC)C=C2OC(C)C)=N[C@H](C3=CC=C(Cl)C=C3)[C@@H]1C4=CC=C(Cl)C=C4)=O)CC5)N5CC(NCCOCCOCCOCCOCCN=[N+]=[N-])=O
• Target: Others,E3 Ligase Ligand-Linker Conjugates,PROTAC Linker

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138911378