NUCC-0226272

SKU: orb2565640

Description

NUCC-0226272 is a potent PROTAC degrader of EZH2, demonstrating anti-proliferative activity in cancer cell lines. It serves as a valuable chemical probe for oncology research, enabling the study of EZH2-dependent mechanisms in both cellular and in vivo models.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3004503-12-9
• MW: 1182.56
• Formula: C₆₇H₉₁N₉O₈S
• SMILES: N(CC)(C1=CC(=CC(C(NCC2=C(C)C=C(C)NC2=O)=O)=C1C)C3=CC=C(CN4CCN(C(CCCCCCCCCC(N[C@H](C(=O)N5[C@H](C(NCC6=CC=C(C=C6)C7=C(C)N=CS7)=O)C[C@@H](O)C5)C(C)(C)C)=O)=O)CC4)C=C3)C8CCOCC8
• Target: Histone Methyltransferase,PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171038189