NSC727447

SKU: orb2565645

Description

NSC727447 is a selective ribonuclease H (RNase H) inhibitor active against HIV-1 and HIV-2, with IC50 values of 2.0 μM and 2.5 μM, respectively. It shows minimal inhibition of E. coli RNase H, highlighting its specificity for the viral enzyme. This small molecule is a valuable research tool for studying HIV reverse transcriptase function and antiviral mechanisms in biochemical assays.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 40106-12-5
• MW: 210.30
• Formula: C₁₀H₁₄N₂OS
• SMILES: C(N)(=O)C=1C2=C(SC1N)CCCCC2
• Target: DNA/RNA Synthesis,HIV Protease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

2997881