NS-062

SKU: orb2802197

Description

NS-062 is an irreversible covalent EGFR inhibitor with potent activity against resistant mutations. It demonstrates in vitro antiproliferative efficacy in H1975 cells (IC50 = 0.19 µM) and has shown in vivo antitumor activity in a murine H1975 xenograft model, supporting its use in oncology research for studying EGFR-driven resistance.

Research Area

Cardiovascular Research, Infectious Disease & Virology, Signal Transduction

Key Properties

• CAS Number: 2226257-92-5
• MW: 623.48
• Formula: C₂₈H₃₀Cl₂F₂N₆O₄
• SMILES: N(C=1C2=C(C=C(OCCCN3CCOCC3)C(NC(=O)[C@@H]4N(C(C(Cl)F)=O)CCC4)=C2)N=CN1)C5=CC(Cl)=C(F)C=C5
• Target: EGFR,Antibacterial

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

134827850