NOX2-IN-2 diTFA

SKU: orb2664934

Description

NOX2-IN-2 diTFA is a potent small molecule inhibitor that disrupts the p47phox-p22phox interaction with a Ki of 0.24 µM, effectively suppressing NOX2-derived reactive oxygen species (ROS) in cellular assays. This compound is a valuable research tool for studying NOX2 function in oxidative stress-related pathologies, including inflammation and ischemia-reperfusion injury, in both in vitro and in vivo models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2648709-80-0
• MW: 699.56
• Formula: C₂₉H₂₇F₆N₇O₇
• SMILES: O=C(C(F)(F)F)O.NC1=CC=C2C(C=CC(OCC3=CN(CCOCCOC4=CC5=CC=C(N)N=C5C=C4)N=N3)=C2)=N1.O=C(C(F)(F)F)O
• Target: NADPH

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156407711