Nonapeptide-1 acetate salt

SKU: orb1981735

Description

Nonapeptide-1 (Melanostatine-5) acetate salt is a peptide hormone that functions as a selective and competitive antagonist of the melanocortin 1 receptor (MC1R) with a binding affinity (K i) of 40 nM. It effectively inhibits α-MSH-induced increases in intracellular cyclic AMP (cAMP) and melanosome dispersion in melanocytes, with inhibitory concentrations (IC 50) of 2.5 nM and 11 nM, respectively. By inhibiting melanin synthesis, Nonapeptide-1 acetate salt is used in research related to skin pigmentation, adrenal gland steroid production regulation, and skin cancer.

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Key Properties

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MW	1266.56
Formula	C₆₃H₉₁N₁₅O₁₁S
Target	Melanocortin Receptor

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

Melanocortin Receptor

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