Noberastine maleate

• Catalog Number: orb1738055
• Category: Small Molecules
• Description: Noberastine maleate
• CAS Number: 111922-05-5
• Purity: 0.98
• MW: 543.53
• Formula: C₂₅H₂₉N₅O₉
• Biological Activity: Noberastine maleate, a histamine H1 antagonist, has potent and specific peripheral antihistaminic activity. Noberastine, a furan derivative of nor-astemizole (an astemizole metabolite), has been shown to have a more rapid onset, and shorter duration of action than astemizole with peak antihistaminic activity at 4h following ingestion. Noberastine is rapidly absorbed and the peak plasma levels are obtained within 2 h of oral dosing. In preclinical studies Noberastine has been shown to lack central nervous system effects. After subacute (steady-state) administration of noberastine, there was increasing inhibition of weal and flare formation with higher doses of the drug. The 30 mg daily dose showed maximum antihistaminic effects.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.