N,N-Dimethylsphingosine

SKU: orb1704319

Description

N,N-Dimethylsphingosine (DMS) is an endogenous, competitive inhibitor of sphingosine kinase (SphK) that selectively blocks sphingosine phosphorylation. Elevated in neuropathic pain models, it is used in research to study mechanisms of mechanical nociception, including the potentiation of IL-1β and MCP-1 release in vitro and in vivo.

Research Area

Cell Biology

Key Properties

• CAS Number: 119567-63-4
• MW: 327.56
• Purity: >98%
• Formula: C₂₀H₄₁NO₂
• SMILES: CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](CO)N(C)C
• Target: Kinase
• Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

5282309