NK314

SKU: orb1739544

Description

NK314 is a synthetic benzo[c]phenanthridine alkaloid with potent antitumor activity, functioning as a topoisomerase II poison that induces rapid, proteinase K-independent DNA cleavage. Its mechanism and efficacy have been studied in vitro and in vivo, supporting its application in cancer research, particularly in investigating DNA damage and chemotherapeutic strategies.

Research Area

Molecular Biology

Key Properties

• CAS Number: 208237-49-4
• MW: 397.85
• Formula: C₂₂H₂₀ClNO₄
• SMILES: [Cl-].COc1ccc2c(c3CCC[n+]3c3c4cc5OCOc5cc4ccc23)c1O
• Target: Others,Topoisomerase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9952584