Nitroxazepine

SKU: orb1309334

Description

Nitroxazepine (CIBA 2330Go) is a tricyclic antidepressant and serotonin-norepinephrine reuptake inhibitor used in depression research. It is applied in neuropharmacology studies for investigating monoamine transporter function in both in vitro binding assays and in vivo animal models of depressive-like behavior.

Research Area

Neuroscience

Key Properties

• CAS Number: 47439-36-1
• MW: 341.36
• Purity: 98.46%
• Formula: C₁₈H₁₉N₃O₄
• SMILES: C(CCN(C)C)N1C=2C(OC=3C(C1=O)=CC(N(=O)=O)=CC3)=CC=CC2
• Target: Serotonin Transporter
• Solubility: DMSO:60 mg/mL (175.77 mM)

Bioactivity

• In Vitro:
  In vitro effect of Nitroxazepine , as a modulator alone and in combination with hydroxyurea (HU), on cytotoxicity is studied in 16 cases of human chronic myeloid leukemia (CML).

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CIBA 2330Go, 5-HTT, Nitroxazepine, inhibit, Inhibitor, SERT, SerotoninTransporter, Serotonin Transporter, serotonin-norepinephrine reuptake, SLC6A4

Compound Identifiers

PubChem CID

27857