Neuroprotective agent 12

SKU: orb3135303

Description

Neuroprotective agent 12 is an orally active compound capable of crossing the blood-brain barrier, offering significant neuroprotective properties. It exhibits robust antioxidant and anti-inflammatory effects, markedly inhibiting cell death induced by glutamate and acrolein. This agent reduces the expression of PDE4B while elevating levels of HO-1, p-CREB, and BDNF. In a traumatic brain injury (TBI) mouse model, Neuroprotective agent 12 demonstrates potent neuroprotection and holds potential for research into TBI and other central nervous system disorders.

Key Properties

• CAS Number: 2522599-69-3
• MW: 380.48
• Formula: C₂₃H₂₈N₂O₃
• SMILES: O(C1=C(OC)C=C(/C=C/C(NC2=CC=C(N(C)C)C=C2)=O)C=C1)C3CCCC3
• Target: NF-κB,PDE,ROS

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

NF-κB,PDE,ROS