Neratinib-d6

SKU: orb3138964

Description

Neratinib-d6 is the deuterated form of Neratinib. Neratinib (HKI-272) is an orally active, irreversible tyrosine kinase inhibitor that suppresses the activity of HER2 and EGFR, with IC50 values of 59 nM and 92 nM, respectively.

Key Properties

• CAS Number: 1259519-18-0
• MW: 563.08
• Formula: C₃₀H₂₉ClN₆O₃
• SMILES: N(C=1C2=C(C=C(OCC)C(NC(/C=C/CN(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)=C2)N=CC1C#N)C3=CC(Cl)=C(OCC4=CC=CC=N4)C=C3
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR