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Catalog Number | orb1305527 |
---|---|
Category | Small Molecules |
Description | Nedaplatin |
CAS Number | 95734-82-0 |
Purity | 98.69% |
MW | 303.17 |
SMILES | [NH3][Pt+2]1([NH3])[O-]C(=O)C[O-]1 |
Formula | C2H8N2O3Pt |
Biological Activity | Nedaplatin (NSC-375101D) is a derivative of cisplatin and DNA damage agent for tumor colony forming units (IC50: 94 μM). Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive platinum complexes that bind to nucleophilic groups in DNA, resulting in intrastrand and interstrand DNA cross-links, apoptosis and cell death. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[95734-82-0] | |
303.17 | |
C2H8N2O3Pt |
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