Necrostatin 2 racemate

SKU: orb1299761

Description

Necrostatin 2 racemate is a potent and selective RIPK1 inhibitor used to investigate necroptosis. This research tool is widely applied in both in vitro cellular assays and in vivo animal models to study inflammatory diseases, ischemic injury, and neurodegenerative conditions.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 852391-15-2
• MW: 277.71
• Purity: 99.69% (May vary between batches)
• Formula: C₁₃H₁₂ClN₃O₂
• SMILES: CN1C(=O)NC(Cc2c[nH]c3c(Cl)cccc23)C1=O
• Target: RIP kinase
• Solubility: DMSO:45 mg/mL (162.04 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (9 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Necrostatin 2 racemate, Necrostatin2, Necrostatin-2, Necrostatin-2 racemate, necrostatin, Necrostatin 1S, Necrostatin 2, necroptosis, Nec-1, Nec-1S, inhibit, Inhibitor, IDO, stable, RIPkinase, RIP kinase, RIPK, RIPK1, Receptor-interacting protein kinases

Compound Identifiers

PubChem CID

643953