NAI-N3

SKU: orb1220258

Description

NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment).(In Vitro):Living cells are treated with the icSHAPE (in vivo click selective 2-hydroxyl acylation and profiling experiment) chemical NAI-N3 followed by selective chemical enrichment of NAI-N3-modified RNA, which provides an improved signal-to-noise ratio compared with similar methods leveraging deep sequencing.

Key Properties

• CAS Number: 1612756-29-2
• MW: 228.21
• Purity: >98% (HPLC)
• Formula: C??H?N?O
• SMILES: O=C(C1=CC=CN=C1CN=[N+]=[N-])N2C=CN=C2
• Solubility: DMSO : ≥ 115 mg/mL (503.92 mM)

Bioactivity

• In Vitro:
  Living cells are treated with the icSHAPE (in vivo click selective 2-hydroxyl acylation and profiling experiment) chemical NAI-N3 followed by selective chemical enrichment of NAI-N3-modified RNA, which provides an improved signal-to-noise ratio compared with similar methods leveraging deep sequencing.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only