Na2+ - Ca2+ Exchanger inhibitory peptide

SKU: orb2942769

Description

The Na+-Ca2+ Exchanger inhibitory peptide (XIP) is a potent, non-competitive inhibitor of the NCX transporter with a Ki of 200 nM. This research tool is widely used in vitro to study calcium handling in cardiac myocytes and neuronal models, as well as in investigations of ischemia-reperfusion injury.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: Na+/Ca2+ Exchanger
• MW: 2413.64
• Formula: C₁₁₂H₁₆₁N₂₇O₃₃
• SMILES: C[C@@H](C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)N

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677234