N6-Methyl-2'-O-methyladenosine

SKU: orb1819315

Description

N6,2′-O-Dimethyladenosine (m6Am) is a reversible RNA modification serving as a substrate for the obesity-linked enzyme FTO. This small molecule is a valuable research tool for studying epitranscriptomic mechanisms in metabolic diseases, applicable in both in vitro and cell-based assays.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 57817-83-1
• MW: 295.29
• Purity: 99.77% (May vary between batches)
• Formula: C₁₂H₁₇N₅O₄
• SMILES: O(C)[C@H]1[C@H](N2C=3C(N=C2)=C(NC)N=CN3)O[C@H](CO)[C@H]1O
• Target: Nucleoside Antimetabolite/Analog,Others
• Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (8.47 mM);DMSO:55 mg/mL (186.26 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Analog, FTO, N6,2′-O-Dimethyladenosine, N6-Methyl-2'-O-methyladenosine, NucleosideAntimetabolite, Nucleoside Antimetabolite/Analog, Nucleoside Antimetabolite

Compound Identifiers

PubChem CID

6453528