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N-desmethyl Rosiglitazone

N-desmethyl Rosiglitazone

Catalog Number: orb1694373

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Catalog Numberorb1694373
CategorySmall Molecules
DescriptionN-desmethyl Rosiglitazone
Purity98.00%
MW343.4
Biological ActivityN-desmethyl Rosiglitazone is a major metabolite of rosiglitazone , a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl rosiglitazone.
CAS Number257892-31-2
FormulaC17H17N3O3S
SMILESO=C1NC(=O)C(Cc2ccc(OCCNc3ccccn3)cc2)S1
Storage-20°C
NoteFor research use only