N-Caffeoyltryptophan

SKU: orb1296873

Description

N-Caffeoyltryptophan

Research Area

Epigenetics & Chromatin, Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 109163-69-1
• MW: 366.37
• Purity: 98.84%
• Formula: C₂₀H₁₈N₂O₅
• SMILES: C([C@H](NC(/C=C/C1=CC(O)=C(O)C=C1)=O)C(O)=O)C=2C=3C(NC2)=CC=CC3
• Target: Phosphatase,glycosidase,Glucosidase,Sirtuin
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.46 mM);DMSO:45 mg/mL (122.83 mM)

Bioactivity

• Target IC50:
  SIRT1:34μM|SIRT2:8.7 μM
• In Vitro:
  In cellular levels,N-Caffeoyltryptophan was able to increase the acetylation of total lysine, cortactin and histone H3 in neuronal NG108-15 cells. In the same cells, the amide also increased the acetylation of lysine (K382) in p53, but not (K305).

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SIRT2, SIRT1, trans-Caffeoyl-L-tryptophan, N Caffeoyltryptophan, NCaffeoyltryptophan, N-Caffeoyltryptophan

Compound Identifiers

PubChem CID

15228042