N-Biotinyl-6-aminohexanoic acid

SKU: orb1307023

Description

N-Biotinyl-6-aminohexanoic acid is a versatile bioconjugation reagent designed for the site-specific N-terminal biotinylation of peptides and proteins. This modification is widely used in applications such as affinity purification, protein immobilization, and detection in both in vitro assays and in vivo research studies.

Research Area

Metabolism Research

Key Properties

• CAS Number: 72040-64-3
• MW: 357.47
• Purity: 98.61% (May vary between batches)
• Formula: C₁₆H₂₇N₃O₄S
• SMILES: C(CCCC(NCCCCCC(O)=O)=O)[C@H]1[C@@]2([C@](CS1)(NC(=O)N2)[H])[H]
• Target: Transferase,Others
• Solubility: DMSO:11 mg/mL (30.77 mM)

Bioactivity

• In Vitro:
  The SERS (surface-enhanced Raman scattering) of cyclohexyl isocyanide that silver nanoparticles modified with N-Biotinyl-6-aminohexanoic acid and cyclohexyl isocyanide can be anchored on a separate biotinylated substrate via the avidin-biotin interaction.Synthesis of p-nitrophenyl N-acetyllactosaminide with β-D-galactosidase, chemical reduction of the p-nitrophenyl group, and sialylation with sialyltransferase. The p-aminophenyl glycosides are successfully biotin-labeled through the coupling with N-Biotinyl-6-aminohexanoic acid to afford biotinylated oligosaccharides with an aminohexanosyl group and phenyl group as the spacers between the biotin and glycan. The biotin-labeled sugars were shown to be useful for immobilization and assay of the carbohydrate-lectin interactions by an optical biosensor based on surface plasmon resonance.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NBiotinyl6aminohexanoic acid, N-Biotinyl-6-aminohexanoic acid, oligosaccharides, inhibit, N Biotinyl 6 aminohexanoic acid, N-(+)-Biotinyl-6-aminohexanoic acid, Inhibitor, biotinylation, coupling

Compound Identifiers

PubChem CID

446905