N-(3-Aminopropyl)cyclohexylamine

SKU: orb1694239

Description

N-(3-Aminopropyl)cyclohexylamine is a selective, competitive inhibitor of spermine synthase. This small molecule is utilized in biochemical research to study polyamine metabolism, particularly in models of neurological disorders, both in vitro and in vivo.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 3312-60-5
• MW: 156.2685
• Purity: 98.05% (May vary between batches)
• Formula: C₉H₂₀N₂
• SMILES: NCCCNC1CCCCC1
• Target: JAK,Others
• Solubility: H2O:95 mg/mL (607.93 mM)

Bioactivity

• In Vitro:
  N-(3-Aminopropyl)cyclohexylamine at concentrations up to 10(-6) M did not affect the neuronal survival, but significantly blocked the survival-promoting effect of spermine (10(-8) M) . APCHA also blocked the spermine-induced promotion of neurite regeneration following axotomy . In primary cultured brain neurons, APCHA works as a spermine antagonist rather than as a spermine synthesis inhibitor .
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cyclohexylamine, neurological disease, neuron, N(3Aminopropyl)cyclohexylamine, N-(3-Aminopropyl)cyclohexylamine, N (3 Aminopropyl)cyclohexylamine, inhibit, Inhibitor

Compound Identifiers

PubChem CID

18718