MS8815

SKU: orb1982727

Description

MS8815 is a potent and selective PROTAC EZH2 degrader with an IC50 of 8.6 nM. It is a valuable research tool for studying triple-negative breast cancer (TNBC), enabling the investigation of EZH2's role in both cellular and animal models of this disease.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2855085-25-3
• MW: 1154.51
• Formula: C₆₅H₈₇N₉O₈S
• SMILES: CCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(CN2CCN(CC2)C(=O)CCCCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)cc1
• Target: PROTACs,Histone Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165368931