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MS8815

SKU: orb1982727

Description

MS8815 is a potent and selective PROTAC EZH2 degrader with an IC50 of 8.6 nM. It is a valuable research tool for studying triple-negative breast cancer (TNBC), enabling the investigation of EZH2's role in both cellular and animal models of this disease.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2855085-25-3
MW1154.51
FormulaC65H87N9O8S
SMILESCCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(CN2CCN(CC2)C(=O)CCCCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)cc1
TargetHistone Methyltransferase,PROTACs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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MS8815 (orb1982727)

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1 mg
$ 500.00
5 mg
$ 1,410.00
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