MS5033

SKU: orb1983054

Description

MS5033 is a potent PROTAC degrader of AKT (protein kinase B) with a DC50 of 430 nM in PC3 cells. This molecule is a valuable chemical tool for investigating AKT-dependent signaling pathways in cancer research, applicable in both cellular and in vivo model studies.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2376137-29-8
• MW: 1044.59
• Formula: C₅₁H₆₆ClN₁₁O₁₁
• SMILES: NC1(CCN(CC1)c1ncnc2[nH]ccc12)C(=O)N[C@@H](CCN1CCN(CC1)C(=O)CCOCCOCCOCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12)c1ccc(Cl)cc1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

139483021