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MS181

SKU: orb3134434

Description

MS181 (compound 1) is an efficient PROTAC degrader that recruits cereblon (CRBN) and binds to the ubiquitin complex polycomb repressive complex 1 (PRC1). It reduces the expression of EED, EZH2, SUZ12, BMI1, and RING1B, and exhibits antiproliferative activity.

Images & Validation

Key Properties

FormulaC39H41N11O6
TargetPROTACs,E1/E2/E3 Enzyme

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

MS181 (orb3134434)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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