MRTX1133

• Catalog Number: orb1298201
• Category: Small Molecules
• Description: MRTX1133
• Purity: 99.06%
• MW: 600.63
• Biological Activity: MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.
• Solubility (25°C): DMSO: 50 mg/mL (83.25 mM), Sonication is recommended
• CAS Number: [2621928-55-8]
• Formula: C₃₃H₃₁F₃N₆O₂
• SMILES: Oc1cc(-c2ncc3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c2F)N2C[C@@H]3CC[C@H](C2)N3)c2c(C#C)c(F)ccc2c1
• Storage: -20°C
• Note: For research use only