MRS4719

• Catalog Number: orb1744157
• Category: Small Molecules
• Description: MRS4719, a potent P2X4 receptor antagonist, exhibits a half-maximal inhibitory concentration (IC50) of 0.503 μM for the human P2X4 receptor. Demonstrating both neuroprotective and neuro-rehabilitative effects, it can decrease infarct volume and brain atrophy in an ischemic stroke model. Additionally, MRS4719 mitigates ATP-induced calcium influx in primary human monocyte-derived macrophages, making it a valuable tool for researching ischemic stroke.
• CAS Number: 2840581-32-8
• Purity: 98.00%
• MW: 504.6
• SMILES: O=C1NC=2C=3C=CC=CC3C=CC2N(C4=CC=NC(=C4)C5=NOC(=S)N5)C(=O)C1.N(CC)(CC)CC
• Formula: C₂₆H₁₃N₅O₃S.C₆H₁₅N
• Biological Activity: MRS4719, a potent P2X4 receptor antagonist, exhibits a half-maximal inhibitory concentration (IC50) of 0.503 μM for the human P2X4 receptor. Demonstrating both neuroprotective and neuro-rehabilitative effects, it can decrease infarct volume and brain atrophy in an ischemic stroke model. Additionally, MRS4719 mitigates ATP-induced calcium influx in primary human monocyte-derived macrophages, making it a valuable tool for researching ischemic stroke.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.