Monascin

SKU: orb1220226

Description

Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor).

Key Properties

• CAS Number: 21516-68-7
• MW: 358.43
• Purity: >98% (HPLC)
• Formula: C??H??O?
• SMILES: O=C([C@@H]1C(CCCCC)=O)O[C@]2(C)[C@]1([H])CC(C=C(/C=C/C)OC3)=C3C2=O
• Solubility: In Vitro: DMSO : 50 mg/mL (139.50 mM)

Bioactivity

• In Vivo:
  Monascin (0.0025% in drinking water; mice) appears effective for the inhibition of UVB-initiated carcinogenesis on mouse skin. Animal model: SENCAR mouse using a UVB irradiation as an initiator and TPA as a promoter. Dosage: 0.0025% in drinking water. Administration: Orally daily for 2 weeks in drinking water. Result: Reduced the number of the papillomas.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only