MLCK inhibitor peptide 18 acetate

SKU: orb1296462

Description

MLCK inhibitor peptide 18 acetate is a cell-permeable, highly selective competitive inhibitor of myosin light chain kinase with an IC50 of 50 nM. It exhibits 4000-fold selectivity over CaM kinase II and no activity against PKA, making it a valuable tool for investigating smooth muscle contraction, endothelial barrier function, and cell motility in both cellular and biochemical assays.

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• Target: Serine/threonin kinase
• MW: 1384.67
• Purity: 99.57% (May vary between batches)
• Formula: C₆₂H₁₀₉N₂₃O₁₃
• SMILES: C1=CC(=CC=C1C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)N)O.CC(=O)O

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Serine kinase, Serinekinase, threonin kinase, threoninkinase, MLCK, MLCK inhibitor peptide 18 Acetate, MLCK inhibitor peptide 18 acetate, MLCK inhibitor peptide 18 acetate(224579-74-2 free base)

Compound Identifiers

PubChem CID

171361654