MK-7246

SKU: orb1679063

Description

MK-7246 is a selective small molecule antagonist of the CRTH2 receptor with a high binding affinity (Ki = 2.5 nM). It is a valuable research tool for investigating the role of CRTH2 in allergic inflammation and asthma, applicable in both in vitro binding assays and in vivo disease models.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1218918-62-7
• MW: 416.47
• Formula: C₂₁H₂₁FN₂O₄S
• SMILES: CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)S(=O)(=O)c1ccc(F)cc1
• Target: Prostaglandin Receptor,GPCR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

45268455