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MK-4541

SKU: orb1744194

Description

MK-4541 is an orally bioavailable selective androgen receptor modulator (SARM) and 5α-reductase antagonist. It demonstrates anti-proliferative and pro-apoptotic activity in AR-positive prostate cancer cells in vitro and has shown efficacy in reducing tumor growth in R3327-G prostate cancer xenograft models in vivo.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number796885-38-6
MW428.49
FormulaC22H31F3N2O3
SMILESC[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@H](NC(OCC(F)(F)F)=O)CC4)[H])(CC[C@]1(N(C)C(=O)C=C2)[H])[H])[H]
TargetAndrogen Receptor,Others,Reductase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

MK-4541 (orb1744194)

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