MK-4074

SKU: orb1709115

Description

MK-4074 is a potent and liver-specific small molecule inhibitor of both acetyl-CoA carboxylase isoforms ACC1 and ACC2, exhibiting an IC50 of 3 nM. It is a valuable research tool for studying hepatic de novo lipogenesis and fatty acid oxidation in models of metabolic diseases, including non-alcoholic fatty liver disease (NAFLD).

Research Area

Metabolism Research

Key Properties

• CAS Number: 1039758-22-9
• MW: 565.62
• Formula: C₃₃H₃₁N₃O₆
• SMILES: COc1cc(cc2n(cc(C)c12)C1CC1)C(=O)N1CCC2(CC1)CC(=O)c1cc(ccc1O2)-c1cncc(c1)C(O)=O
• Target: Others,Acetyl-CoA Carboxylase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

24964679