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MK-0812

SKU: orb1679026

Description

MK-0812 is a potent small molecule dual antagonist of chemokine receptors CCR2 and CCR5. It has demonstrated efficacy in reducing adipose tissue inflammation in ob/ob mouse models, making it a valuable research tool for studying metabolic disease, inflammation, and chemokine receptor biology in both in vitro and in vivo systems.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number624733-88-6
MW469.54
FormulaC24H34F3N3O3
SMILESC(=O)([C@]1([C@H](C)C)C[C@H](N[C@@H]2[C@H](OC)COCC2)CC1)N3CC=4C(CC3)=NC=C(C(F)(F)F)C4
TargetCCR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Key Properties

No computed properties available.

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MK-0812 (orb1679026)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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