MitoBloCK-11 (MB-11)

SKU: orb1298636

Description

MitoBloCK-11 (MB-11) is a small molecule inhibitor that disrupts mitochondrial protein import, specifically targeting the Seo1 transport pathway rather than Tom70/Tom20. It selectively inhibits precursors with hydrophobic segments, a mechanism demonstrated in yeast complementation assays and studies of vertebrate development, including zebrafish embryogenesis.

Research Area

Signal Transduction

Key Properties

• CAS Number: 413606-16-3
• MW: 434.26
• Purity: 99.64% (May vary between batches)
• Formula: C₁₇H₁₂BrN₃O₄S
• SMILES: O(CC(NN=CC=1SC(N(=O)=O)=CC1)=O)C=2C3=C(C(Br)=CC2)C=CC=C3
• Target: PTEN,Others
• Solubility: DMSO:25 mg/mL (57.57 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MitoBloCK 11 (MB 11), MitoBloCK11 (MB11), MitoBloCK-11 (MB-11), mitochondrial protein import

Compound Identifiers

PubChem CID

1381747