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Miriplatin

SKU: orb1223314

Description

Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).

Images & Validation

Key Properties

CAS Number141977-79-9
MW764
Purity>98% (HPLC)
FormulaC34H68N2O4Pt
SMILES[Pt+2].O=C([O-])CCCCCCCCCCCCC.N[C@@H]1CCCC[C@H]1N.[O-]C(=O)CCCCCCCCCCCCC
TargetDopamine Receptor
SolubilityDMF : < 1 mg/mL

Bioactivity

In Vivo
Miriplatin (SM-11355) (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells.
In Vitro
Miriplatin (SM-11355) suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

SM-11355

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Miriplatin (orb1223314)

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200 mg
500 mg
5 mg
$ 90.00
10 mg
$ 110.00
25 mg
$ 140.00
50 mg
$ 180.00
100 mg
$ 270.00