MIND4-19

SKU: orb1297740

Description

MIND4-19 is a potent and selective SIRT2 inhibitor exhibiting antitumor properties. It has been utilized in vitro and in vivo research to study oncology, epigenetics, and neurodegenerative diseases, demonstrating potential in modulating cellular processes like proliferation and migration.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 129544-85-0
• MW: 373.47
• Purity: 99.99% (May vary between batches)
• Formula: C₂₂H₁₉N₃OS
• SMILES: C(Oc1ccccc1)c1nnc(SCc2ccccc2)n1-c1ccccc1
• Target: Sirtuin
• Solubility: DMSO:50 mg/mL (133.88 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.36 mM)

Bioactivity

• Target IC50:
  SIRT2:7.0 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, MIND4-19, Huntington's disease, Inhibitor, 4H 1,2,4 Triazole, 3 (phenoxymethyl) 4 phenyl 5 [(phenylmethyl)thio] , 4H1,2,4Triazole, 3(phenoxymethyl)4phenyl5[(phenylmethyl)thio], SIRT2, Sirtuin

Compound Identifiers

PubChem CID

1162727