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Catalog Number | orb1301090 |
---|---|
Category | Small Molecules |
Description | Milciclib |
Purity | 99.73% |
MW | 460.57 |
Biological Activity | Milciclib (PHA-848125) (PHA-848125) is a potent, ATP-competitive CDK inhibitor for CDK2 with IC50 of 45 nM. It is > 3-fold more selective for CDK2 than CDK1, 2, 4, 5, and 7. Phase 2. |
CAS Number | [802539-81-7] |
Formula | C25H32N8O |
SMILES | CNC(=O)c1nn(C)c-2c1C(C)(C)Cc1cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc-21 |
Storage | -20°C |
Note | For research use only |