MIDD0301 sodium

SKU: orb3028617

Description

MIDD0301 (GL-II-93) sodium is an orally active inhibitor of γ-aminobutyric acid type A receptors (GABAAR) and an anti-asthmatic agent. It shows bio- and immunotoxicological safety in mice without affecting circulating lymphocyte, monocyte, and granulocyte counts. MIDD0301 sodium demonstrates no significant adverse immune responses under repeated dosing and is more favorable than Prednisone. It relaxes histamine-contracted tracheal smooth muscle in guinea pigs and humans, making it a valuable candidate for research in bronchoconstriction-related diseases.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2593569-36-7
• MW: 437.218
• Formula: C₁₉H₁₃BrFN₃NaO₂
• SMILES: C(O)(=O)C1=C2N(C=3C(C(=N[C@@H]2C)C4=C(F)C=CC=C4)=CC(Br)=CC3)C=N1.[Na]
• Target: GABA Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

GABA Receptor