Mibampator

SKU: orb1940713

Description

Mibampator is an effective and selective AMPA receptor potentiator.(In Vivo):Mibampator reverses the central effects of an acutely intoxicating dose of ethanol in rats. Mibampator dose-dependently reverses ethanol-induced deficits in both motor coordination and disruptions in an operant task in the food reward test.

Key Properties

• CAS Number: 375345-95-2
• MW: 438.6
• Purity: >98% (HPLC)
• Formula: C₂₁H₃₀N₂O₄S₂
• SMILES: CC(C)S(=O)(=O)NC[C@H](C)c1ccc(cc1)-c1ccc(CCNS(C)(=O)=O)cc1
• Target: iGluR
• Solubility: In Vitro: DMSO : ≥ 25 mg/mL (57.00 mM)

Bioactivity

• In Vivo:
  Incubation of Mibampator (LY451395) with Actinoplanes missouriensis NRRL B3342 generated several metabolites that were previously detected in In vivo metabolism studies of the preclinical species. LY404187 and Mibampator (LY451395) reverses the central effects of an acutely intoxicating dose of ethanol in the rat. Mibampator (LY451395) significantly and dose-dependently reversed ethanol-induced deficits in both motor coordination and disruptions in an operant task where animals were trained to press a lever for food reward.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

LY451395

Quick Database Links

Gene Symbol

iGluR