Methoxyamine HCl

SKU: orb1306401

Description

Methoxyamine HCl is an orally available small molecule that covalently binds to AP sites in DNA, inhibiting the base excision repair (BER) pathway. This inhibition can enhance DNA damage and apoptosis, particularly in combination with alkylating agents in cancer research, as demonstrated in both in vitro and in vivo studies.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 593-56-6
• MW: 83.51
• Purity: ≥98% (May vary between batches)
• Formula: CH₆ClNO
• SMILES: Cl.CON
• Target: Others
• Solubility: DMSO:55 mg/mL (658.6 mM);H2O:Soluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (23.95 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Methoxyamine, Methoxyamine HCl, TRC 102, TRC102, TRC-102

Compound Identifiers

PubChem CID

521874