MC-Val-Cit-PAB-VX765

SKU: orb2279197

Description

MC-VAL-CIT-PAB-VX765 is a derivative of the cathepsin-cleavable linker VX765, designed for conjugation to antibodies, polymers, or proteins to create targeted therapeutics. This ADC linker enables the specific release of payloads in lysosomes and is widely utilized in the research and development of antibody-drug conjugates for both in vitro and in vivo cancer studies.

Key Properties

• MW: 1107.66
• Formula: C₅₃H₇₁ClN₁₀O₁₄
• SMILES: O=C1C=CC(N1CCCCCC(N[C@H](C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(NC3=CC=C(C(N[C@H](C(N4CCC[C@H]4C(N[C@@H]5[C@H](OCC)OC(C5)=O)=O)=O)C(C)(C)C)=O)C=C3Cl)=O)C=C2)=O)=O)C(C)C)=O)=O
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168012816