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MC-Val-Cit-PAB-vinblastine

SKU: orb1988043

Description

MC-Val-Cit-PAB-vinblastine is an antibody-drug conjugate (ADC) linker-payload featuring the microtubule inhibitor vinblastine. This cleavable conjugate is designed for the development of targeted anticancer therapeutics and is suitable for both in vitro and in vivo research applications investigating ADC efficacy and mechanism.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2055896-92-7
MW1366.644
FormulaC74H97N10O15
SMILES[H][C@@]12N3CC[C@@]11c4cc(c(OC)cc4N(C)[C@@]1([H])[C@](O)([C@H](OC(C)=O)[C@]2(CC)C=CC3)C(=O)OC)[C@]1(C[C@]2([H])C[C@@](O)(CC)C[N@@+](Cc3ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN4C(=O)C=CC4=O)C(C)C)cc3)(C2)CCc2c1[nH]c1ccccc21)C(=O)OC |c:32,82,@:81|
TargetDrug-Linker Conjugates for ADC,PROTAC Linker

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

MC-Val-Cit-PAB-vinblastine (orb1988043)

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