MC-GGFG-AM-(10NH2-11F-Camptothecin)

SKU: orb1942933

Description

MC-GGFG-AM-(10NH2-11F-Camptothecin) is a Trop-2-targeting antibody-drug conjugate (ADC) for research use. It employs the sacituzumab antibody connected via a cleavable, pH-sensitive linker to deliver a camptothecin derivative. This construct is applied in oncology research for investigating ADC mechanisms and efficacy in both cellular and animal tumor models.

Key Properties

• CAS Number: 2873460-71-8
• MW: 892.88
• Formula: C₄₅H₄₅FN₈O₁₁
• SMILES: O=C1N2C(C=3C(C2)=CC=4C(N3)=CC(F)=C(NC(CNC([C@H](CC5=CC=CC=C5)NC(CNC(CNC(CCCCCN6C(=O)C=CC6=O)=O)=O)=O)=O)=O)C4)=CC7=C1COC(=O)[C@]7(CC)O
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168510616