MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin

SKU: orb1984559

Description

MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluorocamptothecin (compound 21a) is a camptothecin-derived cytotoxic payload designed for constructing antibody-drug conjugates (ADCs). This small molecule is used in research for developing targeted cancer therapies, with applications in both in vitro cytotoxicity assays and in vivo preclinical studies of ADC efficacy.

Key Properties

• CAS Number: 2414594-29-7
• MW: 902.934
• Formula: C₄₄H₅₁FN₈O₁₂
• SMILES: CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)cc4c(CNC(=O)COCNC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CCCCCN4C(=O)C=CC4=O)c3Cn1c2=O |c:58|
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156165894