MC-1568

SKU: orb1223853

Description

A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A; displays 176-fold selectivity over HD1-B; increases the accumulation of acetylated H3 and H4 histones in MCF-7 cells at 20 uM; promotes neurite growth and arbourisation and protects neurite arbours against neurotoxic insult.

Key Properties

• CAS Number: 852475-26-4
• MW: 314.311
• Purity: >98% (HPLC)
• Formula: C₁₇H₁₅FN₂O₃
• SMILES: O=C(NO)/C=C/C1=CC=C(/C=C/C(C2=CC=CC(F)=C2)=O)N1C
• Target: HDAC
• Solubility: DMSO: 18.5 mg/mL

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MC1568

Quick Database Links

Gene Symbol

HDAC