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MC-1568

SKU: orb1223853

Description

A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A; displays 176-fold selectivity over HD1-B; increases the accumulation of acetylated H3 and H4 histones in MCF-7 cells at 20 uM; promotes neurite growth and arbourisation and protects neurite arbours against neurotoxic insult.

Images & Validation

Key Properties

CAS Number852475-26-4
MW314.311
Purity>98% (HPLC)
FormulaC17H15FN2O3
SMILESO=C(NO)/C=C/C1=CC=C(/C=C/C(C2=CC=CC(F)=C2)=O)N1C
TargetHDAC
SolubilityDMSO: 18.5 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

MC1568

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    852475-26-4

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MC-1568 (orb1223853)

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Available Sizes

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500 mg
5 mg
$ 70.00
10 mg
$ 100.00
25 mg
$ 150.00
50 mg
$ 220.00
100 mg
$ 370.00
200 mg
$ 610.00